Archived record · Edyssy 2014
Comprehensive Laboratory Animal Monitoring System For Core Facility
- Agency
- NIHNational Institutes of Health
- Principal investigator
- Martin Myers
- Institution
- University of Michigan at Ann Arbor
- Amount listed
- $178,700
- Period
- June 15, 2010 to June 14, 2011
Abstract
DESCRIPTION (provided by applicant): Rodent models of disease, especially genetically-modified mouse models, have provided powerful tools to investigate the processes underlying metabolic diseases, including obesity and Type 2 diabetes. In order to understand the physiology of such models and the alterations in metabolism that underlie their phenotypes, equipment capable of specialized and precise measurements must be employed to examine energy balance and metabolic variables. The Comprehensive Laboratory Animal Monitoring System (CLAMS) continuously and simultaneously monitors activity, feeding, and drinking, as well as VO2 and VCO2 for the determination of metabolic rate and RQ. Our Animal Phenotyping Core facility has a single 8-cage CLAMS that cannot keep pace with the high and accelerating demand for this service; this demand results from the increased number of investigators and mouse models that require this analysis. The current system is also inadequate for the analysis of animal models that employ multiple control groups. The purchase of a second, 12-cage system will permit the analysis of these animal models in a more timely fashion and the two systems together will enable the analysis of up to 20 animals at one time. Animal Model;Animals;Control Groups;Core Facility;Disease;drinking;energy balance;Equipment;feeding;Laboratory Animals;Measurement;Metabolic;Metabolic Diseases;Metabolism;Modeling;Monitor;mouse model;Non-Insulin-Dependent Diabetes Mellitus;Obesity;Phenotype;Physiology;Process;Research Personnel;Rodent Model;Services;System;Time;tool
Reading this record as an applicant
The record names Martin Myers at University of Michigan at Ann Arbor as principal investigator. When a professor holds an award like this, part of the budget usually goes to people: graduate research assistants, a postdoc or a technician. Shorter awards are often one year of a renewing project, so check whether it was continued. Look up the investigator’s current awards before you write; a 2014 record is a lead, not a promise. Before you do, read up on getting into a funded lab with an uneven transcript.
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